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Dual-Fluorophore Quantitative High-throughput Screen for Inhibitors of BRCT-Phosphoprotein Interaction
Finding specific small-molecule inhibitors of protein-protein interactions remains a significant challenge. Recently, attention has grown toward “hot-spot” interactions where binding is dominated by a limited number of amino acid contacts, theoretically offering an increased opportunity for disrupti...
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| 主要な著者: | , , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2007
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3389998/ https://ncbi.nlm.nih.gov/pubmed/18158907 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ab.2007.11.039 |
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