Probing heterotrimeric G protein activation: applications to biased ligands

Cell surface G protein-coupled receptors (GPCRs) drive numerous signaling pathways involved in the regulation of a broad range of physiologic processes. Today, they represent the largest target for modern drugs development with potential application in all clinical fields. Recently, the concept of “...

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Bibliografske podrobnosti
Main Authors: Denis, Colette, Saulière, Aude, Galandrin, Ségolène, Sénard, Jean-Michel, Galés, Céline
Format: Artigo
Jezik:Inglês
Izdano: Bentham Science Publishers 2012
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3389521/
https://ncbi.nlm.nih.gov/pubmed/22229559
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