Bioluminescence Resonance Energy Transfer Assays Reveal Ligand-specific Conformational Changes within Preformed Signaling Complexes Containing δ-Opioid Receptors and Heterotrimeric G Proteins

Heptahelical receptors communicate extracellular information to the cytosolic compartment by binding an extensive variety of ligands. They do so through conformational changes that propagate to intracellular signaling partners as the receptor switches from a resting to an active conformation. This a...

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Detalhes bibliográficos
Main Authors: Audet, Nicolas, Galés, Céline, Archer-Lahlou, Élodie, Vallières, Marc, Schiller, Peter W., Bouvier, Michel, Pineyro, Graciela
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2008
Assuntos:
Mechanisms of Signal Transduction
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3258885/
https://ncbi.nlm.nih.gov/pubmed/18381293
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M707941200
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