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Arylstibonic acids are potent and isoform-selective inhibitors of Cdc25a and Cdc25b phosphatases

Arylstibonates structurally resemble phosphotyrosine side chains in proteins and here we addressed the ability of such compounds to act as inhibitors of a panel of mammalian tyrosine and dual-specificity phosphatases. Two arylstibonates both possessing a carboxylate side chain were identified as pot...

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Detaylı Bibliyografya
Asıl Yazarlar: Mak, Lok Hang, Knott, Jessica, Scott, Katherine A., Scott, Claire, Whyte, Gillian F., Ye, Yu, Mann, David, Ces, Oscar, Stivers, James, Woscholski, Rudiger
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2012
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3389297/
https://ncbi.nlm.nih.gov/pubmed/22705189
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2012.05.040
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