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Dual mode of degradation of Cdc25 A phosphatase
The Cdc25 dual-specificity phosphatases control progression through the eukaryotic cell division cycle by activating cyclin-dependent kinases. Cdc25 A regulates entry into S-phase by dephosphorylating Cdk2, it cooperates with activated oncogenes in inducing transformation and is overexpressed in sev...
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Main Authors: | , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Oxford University Press
2002
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC126287/ https://ncbi.nlm.nih.gov/pubmed/12234927 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/cdf491 |
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