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Characterisation of the PTEN inhibitor VO-OHpic

PTEN (phosphatase and tensin homologue deleted on chromosome 10) is a phosphatidylinositol triphosphate 3-phosphatase that counteracts phosphoinositide 3-kinases and has subsequently been implied as a valuable drug target for diabetes and cancer. Recently, we demonstrated that VO-OHpic is an extreme...

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Bibliographische Detailangaben
Hauptverfasser: Mak, Lok Hang, Vilar, Ramón, Woscholski, Rudiger
Format: Artigo
Sprache:Inglês
Veröffentlicht: Springer-Verlag 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2957887/
https://ncbi.nlm.nih.gov/pubmed/21643420
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12154-010-0041-7
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