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PTEN inhibitor VO-OHpic attenuates inflammatory M1 macrophages and cardiac remodeling in doxorubicin-induced cardiomyopathy
Doxorubicin (Doxo) is an effective agent commonly used in cancer therapeutics. Unfortunately, Doxo treatment can stimulate cardiomyopathy and subsequent heart failure, limiting the use of this drug. The role of phosphatase and tensin homolog (PTEN) in apoptosis has been documented in Doxo-induced ca...
Αποθηκεύτηκε σε:
| Τόπος έκδοσης: | Am J Physiol Heart Circ Physiol |
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| Κύριοι συγγραφείς: | , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
American Physiological Society
2018
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6297808/ https://ncbi.nlm.nih.gov/pubmed/30095997 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00121.2018 |
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