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PTEN inhibitor VO-OHpic attenuates inflammatory M1 macrophages and cardiac remodeling in doxorubicin-induced cardiomyopathy
Doxorubicin (Doxo) is an effective agent commonly used in cancer therapeutics. Unfortunately, Doxo treatment can stimulate cardiomyopathy and subsequent heart failure, limiting the use of this drug. The role of phosphatase and tensin homolog (PTEN) in apoptosis has been documented in Doxo-induced ca...
Shranjeno v:
| izdano v: | Am J Physiol Heart Circ Physiol |
|---|---|
| Main Authors: | , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
American Physiological Society
2018
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6297808/ https://ncbi.nlm.nih.gov/pubmed/30095997 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00121.2018 |
| Oznake: |
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