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Combination therapy with HSP90 inhibitor 17-DMAG reconditions the tumor microenvironment to improve recruitment of therapeutic T cells()

Ineffective recognition of tumor cells by CD8(+) T cells is a limitation of cancer immunotherapy. Therefore, treatment regimens that coordinately promote enhanced anti-tumor CD8(+) T cell activation, delivery, and target cell recognition should yield greater clinical benefit. Using an MCA205 sarcoma...

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Detaylı Bibliyografya
Asıl Yazarlar: Rao, Aparna, Taylor, Jennifer L., Chi-Sabins, Nina, Kawabe, Mayumi, Gooding, William E., Storkus, Walter J.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2012
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3389149/
https://ncbi.nlm.nih.gov/pubmed/22552283
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-12-0538
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