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Combination therapy with HSP90 inhibitor 17-DMAG reconditions the tumor microenvironment to improve recruitment of therapeutic T cells()
Ineffective recognition of tumor cells by CD8(+) T cells is a limitation of cancer immunotherapy. Therefore, treatment regimens that coordinately promote enhanced anti-tumor CD8(+) T cell activation, delivery, and target cell recognition should yield greater clinical benefit. Using an MCA205 sarcoma...
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Главные авторы: | , , , , , |
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Формат: | Artigo |
Язык: | Inglês |
Опубликовано: |
2012
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Предметы: | |
Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3389149/ https://ncbi.nlm.nih.gov/pubmed/22552283 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-12-0538 |
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