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HSP90 inhibitor 17-DMAG enhances EphA2(+) tumor cell recognition by specific CD8(+) T cells

EphA2, a member of the receptor tyrosine kinase (RTK) family, is commonly expressed by a broad range of cancer types, where its level of (over)expression correlates with poor clinical outcome. Since tumor cell expressed EphA2 is a non-mutated “self” protein, specific CD8(+) T cells are subject to se...

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Hlavní autoři: Kawabe, Mayumi, Mandic, Maja, Taylor, Jennifer L., Vasquez, Cecilia A., Wesa, Amy K., Neckers, Leonard M., Storkus, Walter J.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2009
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2745213/
https://ncbi.nlm.nih.gov/pubmed/19690146
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-08-4511
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