Re-engineering aryl methylcarbamates to confer high selectivity for inhibition of Anopheles gambiae vs human acetylcholinesterase

Ítems similars

• Aryl methylcarbamates: potency and selectivity towards wild-type and carbamate-insensitive (G119S) Anopheles gambiae acetylcholinesterase, and toxicity to G3 Strain An. gambiae
  per: Wong, Dawn M., et al.
  Publicat: (2012)
• Select β- and γ-branched 1-alkylpyrazol-4-yl methylcarbamates exhibit high selectivity for inhibition of Anopheles gambiae versus human acetylcholinesterase
  per: Carlier, Paul R., et al.
  Publicat: (2018)
• Difluoromethyl ketones: potent inhibitors of wild type and carbamate-insensitive G119S mutant Anopheles gambiae acetylcholinesterase
  per: Camerino, Eugene, et al.
  Publicat: (2015)
• Crystal structure of acetylcholinesterase catalytic subunits of the malaria vector Anopheles gambiae
  per: Han, Qian, et al.
  Publicat: (2017)
• Select Small Core Structure Carbamates Exhibit High Contact Toxicity to “Carbamate-Resistant” Strain Malaria Mosquitoes, Anopheles gambiae (Akron)
  per: Wong, Dawn M., et al.
  Publicat: (2012)