Select Small Core Structure Carbamates Exhibit High Contact Toxicity to “Carbamate-Resistant” Strain Malaria Mosquitoes, Anopheles gambiae (Akron)

Acetylcholinesterase (AChE) is a proven target for control of the malaria mosquito (Anopheles gambiae). Unfortunately, a single amino acid mutation (G119S) in An. gambiae AChE-1 (AgAChE) confers resistance to the AChE inhibitors currently approved by the World Health Organization for indoor residual...

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Autors principals: Wong, Dawn M., Li, Jianyong, Chen, Qiao-Hong, Han, Qian, Mutunga, James M., Wysinski, Ania, Anderson, Troy D., Ding, Haizhen, Carpenetti, Tiffany L., Verma, Astha, Islam, Rafique, Paulson, Sally L., Lam, Polo C.-H., Totrov, Maxim, Bloomquist, Jeffrey R., Carlier, Paul R.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2012
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3462181/
https://ncbi.nlm.nih.gov/pubmed/23049714
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0046712
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