Loading...
HtrA2 deficiency causes mitochondrial uncoupling through the F(1)F(0)-ATP synthase and consequent ATP depletion
Loss of the mitochondrial protease HtrA2 (Omi) in mice leads to mitochondrial dysfunction, neurodegeneration and premature death, but the mechanism underlying this pathology remains unclear. Using primary cultures from wild-type and HtrA2-knockout mice, we find that HtrA2 deficiency significantly re...
Na minha lista:
| Main Authors: | , , , , , , , , , , , , |
|---|---|
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Nature Publishing Group
2012
|
| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3388244/ https://ncbi.nlm.nih.gov/pubmed/22739987 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2012.77 |
| Tags: |
Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!
|