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Drosophila HtrA2 is dispensable for apoptosis but acts downstream of PINK1 independently from Parkin
High Temperature Requirement A2 (HtrA2/Omi) is a mitochondrial protease that exhibits pro-apoptotic and cell protective properties and has been linked to Parkinson disease (PD). Impaired mitochondrial function is a common trait in PD patients, and is likely to play a significant role in pathogenesis...
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| Main Authors: | , , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2009
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2711053/ https://ncbi.nlm.nih.gov/pubmed/19282869 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2009.23 |
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