Rhomboid-7 and HtrA2/Omi act in a common pathway with the Parkinson’s disease factors Pink1 and Parkin

Parkinson’s disease (PD) is a common neurodegenerative disorder caused by loss of midbrain dopaminergic neurons, the pathogenetic mechanisms of which remain unclear. Mitochondrial dysfunction, which has long been implicated in sporadic PD, has recently been highlighted as a key pathological cause, p...

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Библиографические подробности
Главные авторы: Whitworth, Alexander J., Lee, Jeffrey R., Ho, Venus M.-W., Flick, Robert, Chowdhury, Ruhena, McQuibban, G. Angus
Формат: Artigo
Язык:Inglês
Опубликовано: The Company of Biologists Limited 2008
Предметы:
Research Report
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2562193/
https://ncbi.nlm.nih.gov/pubmed/19048081
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dmm.000109
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