Structural and functional analysis of the PDZ domains of human HtrA1 and HtrA3

High-temperature requirement A (HtrA) and its homologs contain a serine protease domain followed by one or two PDZ domains. Bacterial HtrA proteins and the mitochondrial protein HtrA2/Omi maintain cell function by acting as both molecular chaperones and proteases to manage misfolded proteins. The bi...

Full description

Saved in:
Bibliographic Details
Main Authors: Runyon, Steven T., Zhang, Yingnan, Appleton, Brent A., Sazinsky, Stephen L., Wu, Ping, Pan, Borlan, Wiesmann, Christian, Skelton, Nicholas J., Sidhu, Sachdev S.
Format: Artigo
Language:Inglês
Published: Cold Spring Harbor Laboratory Press 2007
Subjects:
Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2211686/
https://ncbi.nlm.nih.gov/pubmed/17962403
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1110/ps.073049407
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items