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Structural and functional analysis of the ligand specificity of the HtrA2/Omi PDZ domain

The mitochondrial serine protease HtrA2/Omi helps to maintain mitochondrial function by handling misfolded proteins in the intermembrane space. In addition, HtrA2/Omi has been implicated as a proapoptotic factor upon release into the cytoplasm during the cell death cascade. The protein contains a C-...

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Bibliografiska uppgifter
Huvudupphovsmän: Zhang, Yingnan, Appleton, Brent A., Wu, Ping, Wiesmann, Christian, Sidhu, Sachdev S.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Cold Spring Harbor Laboratory Press 2007
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2203379/
https://ncbi.nlm.nih.gov/pubmed/17656586
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1110/ps.072833207
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