A Specificity Map for the PDZ Domain Family

PDZ domains are protein–protein interaction modules that recognize specific C-terminal sequences to assemble protein complexes in multicellular organisms. By scanning billions of random peptides, we accurately map binding specificity for approximately half of the over 330 PDZ domains in the human an...

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Hlavní autoři: Tonikian, Raffi, Zhang, Yingnan, Sazinsky, Stephen L, Currell, Bridget, Yeh, Jung-Hua, Reva, Boris, Held, Heike A, Appleton, Brent A, Evangelista, Marie, Wu, Yan, Xin, Xiaofeng, Chan, Andrew C, Seshagiri, Somasekar, Lasky, Laurence A, Sander, Chris, Boone, Charles, Bader, Gary D, Sidhu, Sachdev S
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2008
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2553845/
https://ncbi.nlm.nih.gov/pubmed/18828675
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.0060239
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