Bayesian Modeling of the Yeast SH3 Domain Interactome Predicts Spatiotemporal Dynamics of Endocytosis Proteins

SH3 domains are peptide recognition modules that mediate the assembly of diverse biological complexes. We scanned billions of phage-displayed peptides to map the binding specificities of the SH3 domain family in the budding yeast, Saccharomyces cerevisiae. Although most of the SH3 domains fall into...

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Detalhes bibliográficos
Main Authors: Tonikian, Raffi, Xin, Xiaofeng, Toret, Christopher P., Gfeller, David, Landgraf, Christiane, Panni, Simona, Paoluzi, Serena, Castagnoli, Luisa, Currell, Bridget, Seshagiri, Somasekar, Yu, Haiyuan, Winsor, Barbara, Vidal, Marc, Gerstein, Mark B., Bader, Gary D., Volkmer, Rudolf, Cesareni, Gianni, Drubin, David G., Kim, Philip M., Sidhu, Sachdev S., Boone, Charles
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2009
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2756588/
https://ncbi.nlm.nih.gov/pubmed/19841731
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.1000218
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