Bayesian Modeling of the Yeast SH3 Domain Interactome Predicts Spatiotemporal Dynamics of Endocytosis Proteins

SH3 domains are peptide recognition modules that mediate the assembly of diverse biological complexes. We scanned billions of phage-displayed peptides to map the binding specificities of the SH3 domain family in the budding yeast, Saccharomyces cerevisiae. Although most of the SH3 domains fall into...

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Autores principales: Tonikian, Raffi, Xin, Xiaofeng, Toret, Christopher P., Gfeller, David, Landgraf, Christiane, Panni, Simona, Paoluzi, Serena, Castagnoli, Luisa, Currell, Bridget, Seshagiri, Somasekar, Yu, Haiyuan, Winsor, Barbara, Vidal, Marc, Gerstein, Mark B., Bader, Gary D., Volkmer, Rudolf, Cesareni, Gianni, Drubin, David G., Kim, Philip M., Sidhu, Sachdev S., Boone, Charles
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2009
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2756588/
https://ncbi.nlm.nih.gov/pubmed/19841731
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.1000218
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