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Prediction and Experimental Characterization of nsSNPs Altering Human PDZ-Binding Motifs
Single nucleotide polymorphisms (SNPs) are a major contributor to genetic and phenotypic variation within populations. Non-synonymous SNPs (nsSNPs) modify the sequence of proteins and can affect their folding or binding properties. Experimental analysis of all nsSNPs is currently unfeasible and ther...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3983204/ https://ncbi.nlm.nih.gov/pubmed/24722214 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0094507 |
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