Structural and functional analysis of the PDZ domains of human HtrA1 and HtrA3

High-temperature requirement A (HtrA) and its homologs contain a serine protease domain followed by one or two PDZ domains. Bacterial HtrA proteins and the mitochondrial protein HtrA2/Omi maintain cell function by acting as both molecular chaperones and proteases to manage misfolded proteins. The bi...

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Detalhes bibliográficos
Main Authors: Runyon, Steven T., Zhang, Yingnan, Appleton, Brent A., Sazinsky, Stephen L., Wu, Ping, Pan, Borlan, Wiesmann, Christian, Skelton, Nicholas J., Sidhu, Sachdev S.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2007
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2211686/
https://ncbi.nlm.nih.gov/pubmed/17962403
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1110/ps.073049407
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