Perk-dependent repression of miR-106b-25 cluster is required for ER stress-induced apoptosis

Activation of the unfolded protein response sensor PKR-like endoplasmic reticulum kinase (Perk) attenuates endoplasmic reticulum (ER) stress levels. Conversantly, if the damage is too severe and ER function cannot be restored, this signaling branch triggers apoptosis. Bcl-2 homology 3-only family me...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
Main Authors: Gupta, S, Read, D E, Deepti, A, Cawley, K, Gupta, A, Oommen, D, Verfaillie, T, Matus, S, Smith, M A, Mott, J L, Agostinis, P, Hetz, C, Samali, A
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2012
Teme:
Original Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3388242/
https://ncbi.nlm.nih.gov/pubmed/22739985
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2012.74
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki