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Widespread PERK-dependent repression of ER targets in response to ER stress
The UPR (Unfolded Protein Response) is a well-orchestrated response to ER protein folding and processing overload, integrating both transcriptional and translational outputs. Its three arms in mammalian cells, the PERK translational response arm, together with the ATF6 and IRE1-XBP1-mediated transcr...
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| Udgivet i: | Sci Rep |
|---|---|
| Main Authors: | , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Nature Publishing Group UK
2019
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6416471/ https://ncbi.nlm.nih.gov/pubmed/30867432 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-38705-5 |
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