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Widespread PERK-dependent repression of ER targets in response to ER stress
The UPR (Unfolded Protein Response) is a well-orchestrated response to ER protein folding and processing overload, integrating both transcriptional and translational outputs. Its three arms in mammalian cells, the PERK translational response arm, together with the ATF6 and IRE1-XBP1-mediated transcr...
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| Publicado no: | Sci Rep |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6416471/ https://ncbi.nlm.nih.gov/pubmed/30867432 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-38705-5 |
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