Alternative Immunomodulatory Strategies for Xenotransplantation: CD40/154 Pathway-sparing Regimens Promote Xenograft Survival

Immunosuppressive therapies that block the CD40/CD154 costimulatory pathway have proven to be uniquely effective in preclinical xenotransplant models. Given the challenges facing clinical translation of CD40/CD154 pathway blockade, we examined the efficacy and tolerability of CD40/CD154 pathway-spar...

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Autori principali: Thompson, P, Badell, IR, Lowe, M, Turner, A, Cano, J, Avila, J, Azimzadeh, A, Cheng, X, Pierson, R, Johnson, B, Robertson, J, Song, M, Leopardi, F, Strobert, E, Korbutt, G, Rayat, G, Rajotte, R, Larsen, CP, Kirk, AD
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2012
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3387302/
https://ncbi.nlm.nih.gov/pubmed/22458586
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1600-6143.2012.04031.x
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