Short-Term Administrations of a Combination of Anti–LFA-1 and Anti-CD154 Monoclonal Antibodies Induce Tolerance to Neonatal Porcine Islet Xenografts in Mice

OBJECTIVE: The objective of this study was to determine whether tolerance to neonatal porcine islet (NPI) xenografts could be achieved by short-term administrations of anti–LFA-1 and anti-CD154 monoclonal antibodies (mAbs). RESEARCH DESIGN AND METHODS: Diabetic B6 mice received NPI transplants and s...

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Autori principali: Arefanian, Hossein, Tredget, Eric B., Rajotte, Ray V., Gill, Ron G., Korbutt, Gregory S., Rayat, Gina R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Diabetes Association 2010
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Original Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2844843/
https://ncbi.nlm.nih.gov/pubmed/20086231
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db09-0413
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