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Genomics-aided structure prediction
We introduce a theoretical framework that exploits the ever-increasing genomic sequence information for protein structure prediction. Structure-based models are modified to incorporate constraints by a large number of non-local contacts estimated from direct coupling analysis (DCA) of co-evolving ge...
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| Hauptverfasser: | , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
National Academy of Sciences
2012
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3387073/ https://ncbi.nlm.nih.gov/pubmed/22691493 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1207864109 |
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