Cardiac Kallikrein-Kinin System Is Upregulated in Chronic Volume Overload and Mediates an Inflammatory Induced Collagen Loss

BACKGROUND: The clinical problem of a “pure volume overload” as in isolated mitral or aortic regurgitation currently has no documented medical therapy that attenuates collagen loss and the resultant left ventricular (LV) dilatation and failure. Here, we identify a potential mechanism related to upre...

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Detaylı Bibliyografya
Asıl Yazarlar: Wei, Chih-Chang, Chen, Yuanwen, Powell, Lindsay C., Zheng, Junying, Shi, Ke, Bradley, Wayne E., Powell, Pamela C., Ahmad, Sarfaraz, Ferrario, Carlos M., Dell’Italia, Louis J.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2012
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3387019/
https://ncbi.nlm.nih.gov/pubmed/22768235
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0040110
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