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Increased fibroblast chymase production mediates procollagen autophagic digestion in volume overload
BACKGROUND: Previous work has identified mast cells as the major source of chymase largely associated with a profibrotic phenotype. We recently reported increased fibroblast autophagic procollagen degradation in a rat model of pure volume overload (VO). Here we demonstrate a connection between incre...
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| Gepubliceerd in: | J Mol Cell Cardiol |
|---|---|
| Hoofdauteurs: | , , , , , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
2016
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5198899/ https://ncbi.nlm.nih.gov/pubmed/26807691 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yjmcc.2016.01.019 |
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