Loss of Interstitial Collagen Causes Structural and Functional Alterations of Cardiomyocyte Subsarcolemmal Mitochondria in Acute Volume Overload

Volume overload (VO) caused by aortocaval fistula (ACF) is associated with oxidative/inflammatory stress. The resulting inflammation, matrix metalloproteinase (MMP) activation, and collagen degradation is thought to play a pivotal role in left ventricular (LV) dilatation and failure. Since mitochond...

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Main Authors: Ulasova, Elena, Gladden, James D, Chen, Yuanwen, Zheng, Junying, Pat, Betty, Bradley, Wayne, Powell, Pamela, Zmijewski, Jaroslaw W, Zelickson, Blake R, Ballinger, Scott W, Darley-Usmar, Victor, Dell’Italia, Louis J
Format: Artigo
Jezik:Inglês
Izdano: 2010
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3092361/
https://ncbi.nlm.nih.gov/pubmed/21059354
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yjmcc.2010.10.034
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