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Adenosine A(2A) Receptor Activation Prevents Wear Particle-Induced Osteolysis
Prosthesis loosening, associated with wear-particle–induced inflammation and osteoclast-mediated bone destruction, is a common cause for joint implant failure, leading to revision surgery. Adenosine A(2A) receptors (A(2A)R) mediate potent anti-inflammatory effects in many tissues and prevent osteocl...
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| Autores principales: | , , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2012
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3386559/ https://ncbi.nlm.nih.gov/pubmed/22623741 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.3003393 |
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