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Adenosine A(2A) Receptor Activation Prevents Wear Particle-Induced Osteolysis

Prosthesis loosening, associated with wear-particle–induced inflammation and osteoclast-mediated bone destruction, is a common cause for joint implant failure, leading to revision surgery. Adenosine A(2A) receptors (A(2A)R) mediate potent anti-inflammatory effects in many tissues and prevent osteocl...

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Bibliografski detalji
Glavni autori: Mediero, Aránzazu, Frenkel, Sally R., Wilder, Tuere, He, Wenjie, Mazumder, Amitabha, Cronstein, Bruce N.
Format: Artigo
Jezik:Inglês
Izdano: 2012
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3386559/
https://ncbi.nlm.nih.gov/pubmed/22623741
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.3003393
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