Functional genomics identifies therapeutic targets for MYC-driven cancer

MYC oncogene family members are broadly implicated in human cancers, yet are considered “undruggable” as they encode transcription factors. MYC also carries out essential functions in proliferative tissues, suggesting that its inhibition could cause severe side effects. We elected to identify synthe...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Toyoshima, Masafumi, Howie, Heather L., Imakura, Maki, Walsh, Ryan M., Annis, James E., Chang, Aaron N., Frazier, Jason, Chau, B. Nelson, Loboda, Andrey, Linsley, Peter S., Cleary, Michele A., Park, Julie R., Grandori, Carla
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: National Academy of Sciences 2012
Θέματα:
Biological Sciences
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3386069/
https://ncbi.nlm.nih.gov/pubmed/22623531
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1121119109
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