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Synthetic Lethal Screens as a Means to Understand and Treat MYC-Driven Cancers
Although therapeutics against MYC could potentially be used against a wide range of human cancers, MYC-targeted therapies have proven difficult to develop. The convergence of breakthroughs in human genomics and in gene silencing using RNA interference (RNAi) have recently allowed functional interrog...
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| Autors principals: | , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Cold Spring Harbor Laboratory Press
2014
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3935389/ https://ncbi.nlm.nih.gov/pubmed/24591535 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/cshperspect.a014209 |
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