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Modeling disease mutations by gene targeting in one-cell mouse embryos
Gene targeting by zinc-finger nucleases in one-cell embryos provides an expedite mutagenesis approach in mice, rats, and rabbits. This technology has been recently used to create knockout and knockin mutants through the deletion or insertion of nucleotides. Here we apply zinc-finger nucleases in one...
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| Asıl Yazarlar: | , , , , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
National Academy of Sciences
2012
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3386067/ https://ncbi.nlm.nih.gov/pubmed/22660928 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1121203109 |
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