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Highly Efficient Targeted Mutagenesis in Mice Using TALENs
Targeted mouse mutants are instrumental for the analysis of gene function in health and disease. We recently provided proof-of-principle for the fast-track mutagenesis of the mouse genome, using transcription activator-like effector nucleases (TALENs) in one-cell embryos. Here we report a routine pr...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Genetics Society of America
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3813858/ https://ncbi.nlm.nih.gov/pubmed/23979585 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.113.156570 |
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