Wordt geladen...
Development of an intein-mediated split–Cas9 system for gene therapy
Using CRISPR/Cas9, it is possible to target virtually any gene in any organism. A major limitation to its application in gene therapy is the size of Cas9 (>4 kb), impeding its efficient delivery via recombinant adeno-associated virus (rAAV). Therefore, we developed a split–Cas9 system, bypassing...
Bewaard in:
| Gepubliceerd in: | Nucleic Acids Res |
|---|---|
| Hoofdauteurs: | , , , , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
Oxford University Press
2015
|
| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4513872/ https://ncbi.nlm.nih.gov/pubmed/26082496 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv601 |
| Tags: |
Voeg label toe
Geen labels, Wees de eerste die dit record labelt!
|