A carregar...
Development of an intein-mediated split–Cas9 system for gene therapy
Using CRISPR/Cas9, it is possible to target virtually any gene in any organism. A major limitation to its application in gene therapy is the size of Cas9 (>4 kb), impeding its efficient delivery via recombinant adeno-associated virus (rAAV). Therefore, we developed a split–Cas9 system, bypassing...
Na minha lista:
| Publicado no: | Nucleic Acids Res |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2015
|
| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4513872/ https://ncbi.nlm.nih.gov/pubmed/26082496 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv601 |
| Tags: |
Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!
|