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Nascent RNA structure modulates the transcriptional dynamics of RNA polymerases
RNA polymerase pausing represents an important mechanism of transcriptional regulation. In this study, we use a single-molecule transcription assay to investigate the effect of template base-pair composition on pausing by RNA polymerase II and the evolutionarily distinct mitochondrial polymerase Rpo...
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| Auteurs principaux: | , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
National Academy of Sciences
2012
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3384149/ https://ncbi.nlm.nih.gov/pubmed/22615360 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1205063109 |
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