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LINE-1 hypomethylation in familial and sporadic cancer

Increased and decreased methylation at specific sequences (hypermethylation and hypomethylation, respectively) is characteristic of tumor DNA compared to normal DNA and promotes carcinogenesis in multiple ways including genomic instability. Long interspersed element (LINE), an abundant class of retr...

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Detalhes bibliográficos
Main Authors: Pavicic, Walter, Joensuu, Emmi I., Nieminen, Taina, Peltomäki, Päivi
Formato: Artigo
Idioma:Inglês
Publicado em: Springer-Verlag 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3383956/
https://ncbi.nlm.nih.gov/pubmed/22228215
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00109-011-0854-z
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