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LINE-1 hypomethylation in familial and sporadic cancer

Increased and decreased methylation at specific sequences (hypermethylation and hypomethylation, respectively) is characteristic of tumor DNA compared to normal DNA and promotes carcinogenesis in multiple ways including genomic instability. Long interspersed element (LINE), an abundant class of retr...

詳細記述

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書誌詳細
主要な著者: Pavicic, Walter, Joensuu, Emmi I., Nieminen, Taina, Peltomäki, Päivi
フォーマット: Artigo
言語:Inglês
出版事項: Springer-Verlag 2012
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3383956/
https://ncbi.nlm.nih.gov/pubmed/22228215
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00109-011-0854-z
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