Altered Methylation at MicroRNA-Associated CpG Islands in Hereditary and Sporadic Carcinomas: A Methylation-Specific Multiplex Ligation-Dependent Probe Amplification (MS-MLPA)-Based Approach

MicroRNAs (miRNAs) are small noncoding RNAs that contribute to tumorigenesis by acting as oncogenes or tumor suppressor genes and may be important in the diagnosis, prognosis and treatment of cancer. Many miRNA genes have associated CpG islands, suggesting epigenetic regulation of their expression....

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Main Authors: Pavicic, Walter, Perkiö, Esa, Kaur, Sippy, Peltomäki, Päivi
Formato: Artigo
Idioma:Inglês
Publicado: ScholarOne 2011
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3146601/
https://ncbi.nlm.nih.gov/pubmed/21327300
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2119/molmed.2010.00239
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