Pseudoexons provide a mechanism for allele-specific expression of APC in familial adenomatous polyposis

Allele-specific expression (ASE) of the Adenomatous Polyposis Coli (APC) gene occurs in up to one-third of families with adenomatous polyposis (FAP) that have screened mutation-negative by conventional techniques. To advance our understanding of the genomic basis of this phenomenon, 54 APC mutation-...

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Publicat a:Oncotarget
Autors principals: Nieminen, Taina T., Pavicic, Walter, Porkka, Noora, Kankainen, Matti, Järvinen, Heikki J., Lepistö, Anna, Peltomäki, Päivi
Format: Artigo
Idioma:Inglês
Publicat: Impact Journals LLC 2016
Matèries:
Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5342583/
https://ncbi.nlm.nih.gov/pubmed/27683109
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.12206
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