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Loss of heterozygosity in 7q myeloid disorders: clinical associations and genomic pathogenesis
Loss of heterozygosity affecting chromosome 7q is common in acute myeloid leukemia and myelodysplastic syndromes, pointing toward the essential role of this region in disease phenotype and clonal evolution. The higher resolution offered by recently developed genomic platforms may be used to establis...
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| Main Authors: | , , , , , , , , , , , , , , , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society of Hematology
2012
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3383019/ https://ncbi.nlm.nih.gov/pubmed/22553315 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2011-12-397620 |
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