Spliceosomal gene mutations are frequent events in the diverse mutational spectrum of chronic myelomonocytic leukemia but largely absent in juvenile myelomonocytic leukemia

Chronic myelomonocytic leukemia is a heterogeneous disease with multifactorial molecular pathogenesis. Various recurrent somatic mutations have been detected alone or in combination in chronic myelomonocytic leukemia. Recently, recurrent mutations in spliceosomal genes have been discovered. We inves...

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Autori principali: Kar, Sarah Abu, Jankowska, Anna, Makishima, Hideki, Visconte, Valeria, Jerez, Andres, Sugimoto, Yuka, Muramatsu, Hideki, Traina, Fabiola, Afable, Manuel, Guinta, Kathryn, Tiu, Ramon V., Przychodzen, Bartlomiej, Sakaguchi, Hirotoshi, Kojima, Seiji, Sekeres, Mikkael A., List, Alan F., McDevitt, Michael A., Maciejewski, Jaroslaw P.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Ferrata Storti Foundation 2013
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Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3533671/
https://ncbi.nlm.nih.gov/pubmed/22773603
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2012.064048
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