Mutational spectrum analysis of chronic myelomonocytic leukemia includes genes associated with epigenetic regulation: UTX, EZH2, and DNMT3A

Chronic myelomonocytic leukemia (CMML), a myelodysplastic/myeloproliferative neoplasm, is characterized by monocytic proliferation, dysplasia, and progression to acute myeloid leukemia. CMML has been associated with somatic mutations in diverse recently identified genes. We analyzed 72 well-characte...

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Main Authors: Jankowska, Anna M., Makishima, Hideki, Tiu, Ramon V., Szpurka, Hadrian, Huang, Yun, Traina, Fabiola, Visconte, Valeria, Sugimoto, Yuka, Prince, Courtney, O'Keefe, Christine, Hsi, Eric D., List, Alan, Sekeres, Mikkael A., Rao, Anjana, McDevitt, Michael A., Maciejewski, Jaroslaw P.
Formato: Artigo
Idioma:Inglês
Publicado: American Society of Hematology 2011
Assuntos:
Myeloid Neoplasia
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3193268/
https://ncbi.nlm.nih.gov/pubmed/21828135
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2010-10-311019
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