Mutational spectrum analysis of chronic myelomonocytic leukemia includes genes associated with epigenetic regulation: UTX, EZH2, and DNMT3A

Chronic myelomonocytic leukemia (CMML), a myelodysplastic/myeloproliferative neoplasm, is characterized by monocytic proliferation, dysplasia, and progression to acute myeloid leukemia. CMML has been associated with somatic mutations in diverse recently identified genes. We analyzed 72 well-characte...

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Autori principali: Jankowska, Anna M., Makishima, Hideki, Tiu, Ramon V., Szpurka, Hadrian, Huang, Yun, Traina, Fabiola, Visconte, Valeria, Sugimoto, Yuka, Prince, Courtney, O'Keefe, Christine, Hsi, Eric D., List, Alan, Sekeres, Mikkael A., Rao, Anjana, McDevitt, Michael A., Maciejewski, Jaroslaw P.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society of Hematology 2011
Soggetti:
Myeloid Neoplasia
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3193268/
https://ncbi.nlm.nih.gov/pubmed/21828135
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2010-10-311019
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