Loss of heterozygosity 4q24 and TET2 mutations associated with myelodysplastic/myeloproliferative neoplasms

Chromosomal abnormalities are frequent in myeloid malignancies, but in most cases of myelodysplasia (MDS) and myeloproliferative neoplasms (MPN), underlying pathogenic molecular lesions are unknown. We identified recurrent areas of somatic copy number–neutral loss of heterozygosity (LOH) and deletio...

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Main Authors:	Jankowska, Anna M., Szpurka, Hadrian, Tiu, Ramon V., Makishima, Hideki, Afable, Manuel, Huh, Jungwon, O'Keefe, Christine L., Ganetzky, Rebecca, McDevitt, Michael A., Maciejewski, Jaroslaw P.
Format:	Artigo
Language:	Inglês
Published:	American Society of Hematology 2009
Subjects:	Myeloid Neoplasia
Online Access:	https://ncbi.nlm.nih.gov/pmc/articles/PMC2710933/ https://ncbi.nlm.nih.gov/pubmed/19372255 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2009-02-205690
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Loss of heterozygosity 4q24 and TET2 mutations associated with myelodysplastic/myeloproliferative neoplasms

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