Loss of heterozygosity 4q24 and TET2 mutations associated with myelodysplastic/myeloproliferative neoplasms

Chromosomal abnormalities are frequent in myeloid malignancies, but in most cases of myelodysplasia (MDS) and myeloproliferative neoplasms (MPN), underlying pathogenic molecular lesions are unknown. We identified recurrent areas of somatic copy number–neutral loss of heterozygosity (LOH) and deletio...

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書誌詳細
主要な著者: Jankowska, Anna M., Szpurka, Hadrian, Tiu, Ramon V., Makishima, Hideki, Afable, Manuel, Huh, Jungwon, O'Keefe, Christine L., Ganetzky, Rebecca, McDevitt, Michael A., Maciejewski, Jaroslaw P.
フォーマット: Artigo
言語:Inglês
出版事項: American Society of Hematology 2009
主題:
Myeloid Neoplasia
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2710933/
https://ncbi.nlm.nih.gov/pubmed/19372255
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2009-02-205690
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