CBL, CBLB, TET2, ASXL1, and IDH1/2 mutations and additional chromosomal aberrations constitute molecular events in chronic myelogenous leukemia

Progression of chronic myelogenous leukemia (CML) to accelerated (AP) and blast phase (BP) is because of secondary molecular events, as well as additional cytogenetic abnormalities. On the basis of the detection of JAK2, CBL, CBLB, TET2, ASXL1, and IDH1/2 mutations in myelodysplastic/myeloproliferat...

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Detalhes bibliográficos
Main Authors: Makishima, Hideki, Jankowska, Anna M., McDevitt, Michael A., O'Keefe, Christine, Dujardin, Simon, Cazzolli, Heather, Przychodzen, Bartlomiej, Prince, Courtney, Nicoll, John, Siddaiah, Harish, Shaik, Mohammed, Szpurka, Hadrian, Hsi, Eric, Advani, Anjali, Paquette, Ronald, Maciejewski, Jaroslaw P.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2011
Assuntos:
Myeloid Neoplasia
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3110035/
https://ncbi.nlm.nih.gov/pubmed/21346257
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2010-06-292433
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