CBL, CBLB, TET2, ASXL1, and IDH1/2 mutations and additional chromosomal aberrations constitute molecular events in chronic myelogenous leukemia

Progression of chronic myelogenous leukemia (CML) to accelerated (AP) and blast phase (BP) is because of secondary molecular events, as well as additional cytogenetic abnormalities. On the basis of the detection of JAK2, CBL, CBLB, TET2, ASXL1, and IDH1/2 mutations in myelodysplastic/myeloproliferat...

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Détails bibliographiques
Auteurs principaux: Makishima, Hideki, Jankowska, Anna M., McDevitt, Michael A., O'Keefe, Christine, Dujardin, Simon, Cazzolli, Heather, Przychodzen, Bartlomiej, Prince, Courtney, Nicoll, John, Siddaiah, Harish, Shaik, Mohammed, Szpurka, Hadrian, Hsi, Eric, Advani, Anjali, Paquette, Ronald, Maciejewski, Jaroslaw P.
Format: Artigo
Langue:Inglês
Publié: American Society of Hematology 2011
Sujets:
Myeloid Neoplasia
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3110035/
https://ncbi.nlm.nih.gov/pubmed/21346257
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2010-06-292433
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