Spliceosomal gene mutations are frequent events in the diverse mutational spectrum of chronic myelomonocytic leukemia but largely absent in juvenile myelomonocytic leukemia

Chronic myelomonocytic leukemia is a heterogeneous disease with multifactorial molecular pathogenesis. Various recurrent somatic mutations have been detected alone or in combination in chronic myelomonocytic leukemia. Recently, recurrent mutations in spliceosomal genes have been discovered. We inves...

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Autors principals: Kar, Sarah Abu, Jankowska, Anna, Makishima, Hideki, Visconte, Valeria, Jerez, Andres, Sugimoto, Yuka, Muramatsu, Hideki, Traina, Fabiola, Afable, Manuel, Guinta, Kathryn, Tiu, Ramon V., Przychodzen, Bartlomiej, Sakaguchi, Hirotoshi, Kojima, Seiji, Sekeres, Mikkael A., List, Alan F., McDevitt, Michael A., Maciejewski, Jaroslaw P.
Format: Artigo
Idioma:Inglês
Publicat: Ferrata Storti Foundation 2013
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Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3533671/
https://ncbi.nlm.nih.gov/pubmed/22773603
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2012.064048
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