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Mutations in the spliceosome machinery, a novel and ubiquitous pathway in leukemogenesis
Myelodysplastic syndromes (MDSs) are chronic and often progressive myeloid neoplasms associated with remarkable heterogeneity in the histomorphology and clinical course. Various somatic mutations are involved in the pathogenesis of MDS. Recently, mutations in a gene encoding a spliceosomal protein,...
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| Main Authors: | , , , , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
American Society of Hematology
2012
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3321850/ https://ncbi.nlm.nih.gov/pubmed/22323480 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2011-12-399774 |
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