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Emerging roles of the spliceosomal machinery in myelodysplastic syndromes and other hematologic disorders
In humans, the majority of all protein-coding transcripts contain introns that are removed by mRNA splicing carried out by spliceosomes. Mutations in the spliceosome machinery have recently been identified using whole exome/genome technologies in myelodysplastic syndromes (MDS) and in other hematolo...
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| Главные авторы: | , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2012
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3645466/ https://ncbi.nlm.nih.gov/pubmed/22678168 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/leu.2012.130 |
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