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Emerging roles of the spliceosomal machinery in myelodysplastic syndromes and other hematologic disorders

In humans, the majority of all protein-coding transcripts contain introns that are removed by mRNA splicing carried out by spliceosomes. Mutations in the spliceosome machinery have recently been identified using whole exome/genome technologies in myelodysplastic syndromes (MDS) and in other hematolo...

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Библиографические подробности
Главные авторы: Visconte, V, Makishima, H, Maciejewski, JP, Tiu, RV
Формат: Artigo
Язык:Inglês
Опубликовано: 2012
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3645466/
https://ncbi.nlm.nih.gov/pubmed/22678168
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/leu.2012.130
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